D4 GDI (cleaved specific) antibody [97A1015]

GeneTex

D4 GDI (cleavage specific) antibody [97A1015] - Orthogonal Validated

9

WB: 2 microg/ml. IHC-P: 1:10 - 1:500. FACS: 0.5 - 1 microg / 106 cells. IP: 1 - 2 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

97A1015

0.5 mg/ml

Unconjugated

ARHGDIB

Rho GDP dissociation inhibitor beta

D4; GDIA2; GDID4; LYGDI; Ly-GDI; RAP1GN1; Rho GDI 2; Rho GDP dissociation inhibitor (GDI) beta; rho GDP-dissociation inhibitor 2; rho-GDI beta; RhoGDI2

Mouse

IgG2b

Rho GDP-dissociation inhibitor 2

Members of the Rho (or ARH) protein family (see MIM 165390) and other Ras-related small GTP-binding proteins (see MIM 179520) are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases (summary by Scherle et al., 1993 [PubMed 8356058]).[supplied by OMIM]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203