D5D-IN-326 [1236767-85-3]

MedChem Express

D5D-IN-326 [1236767-85-3]

9

1236767-85-3

Research Use Only

99.90

C17H11F8N3O4

473.27

D5D-IN-326 is a selective, orally active delta-5 desaturase (D5D) inhibitor, with IC50s of 72 and 22 nM for rat and human D5D in enzymic and cell-based assays, respectively, has no effect on D6D or D9D activity. D5D-IN-326 reduces insulin resistance and decreases body weight in diet-induced obese C57BL/6J mice[1].

O=C1C2=C(N=C(N1C3=CC=C(C=C3)OCC(F)(F)F)OCC(F)(C(F)(F)F)F)NC(C2)=O

-20°C,2°C to 8°C

12352200