Bio-Connect

DA-PROTAC [2488660-12-2]

HY-147373
MedChem Express
CAS Number2488660-12-2
Product group Chemicals
Molecular Weight1010.96
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DA-PROTAC [2488660-12-2]
  • Delivery Days Customer
    10
  • CAS Number
    2488660-12-2
  • Certification
    Research Use Only
  • Molecular Formula
    C46H50BrF2N7O8S2
  • Molecular Weight
    1010.96
  • Scientific Description
    DA-PROTAC is a potent PROTAC degrader of copper ion-transport proteins Atox1 and CCS. DA-PROTAC can bind both Atox1 and CCS proteins, and the complex can be bound to E3 ligase, leading to increased levels of ubiquitination of Atox1 and CCS and degradation of Atox1 and CCS proteins via the proteasome pathway. DA-PROTAC can be used for triple negative breast cancer research[1].
  • SMILES
    O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(N=CS3)C)C=C2)=O)C(C(C)(C)C)NC(COCCCOCC(NC4=C(C(NC5=C(C=C(C=C5F)F)Br)=O)SC6=C4C=C(CCC7)C7=N6)=O)=O
  • UNSPSC
    12131703