Dabcyl-YVADAPV-EDANS [161877-70-9]

MedChem Express

Dabcyl-YVADAPV-EDANS [161877-70-9]

14

161877-70-9

Research Use Only

C61H76N12O14S

1233.39

Dabcyl-YVADAPV-EDANS is a fluorogenic interleukin-1beta converting enzyme (ICE) substrate for measuring ICE-like protease activity. Dabcyl-YVADAPV-EDANS detects fluorescence at 360 nm excitation and 480 nm emission wavelengths. ICE-like protease is a critical mediator of K+ deprivation-induced apoptosis of cerebellar granule neurons[1].

O=S(O)(C1=CC=CC2=C1C=CC=C2NCCNC([C@H](C(C)C)NC([C@H]3N(CCC3)C([C@H](C)NC([C@H](CC(O)=O)NC([C@H](C)NC([C@H](C(C)C)NC([C@@H](NC(C4=CC=C(C=C4)/N=N/C5=CC=C(C=C5)N(C)C)=O)CC6=CC=C(C=C6)O)=O)=O)=O)=O)=O)=O)=O)=O

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