Dabrafenib-d9

MedChem Express

Dabrafenib-d9 [1423119-98-5]

10

1423119-98-5

Research Use Only

C23H11D9F3N5O2S2

528.62

Dabrafenib-d 9 is the deuterium labeled Dabrafenib. Dabrafenib (GSK2118436A) is an ATP-competitive inhibitor of Raf with IC50s of 5 nM and 0.6 nM for C-Raf and B-RafV600E, respectively[4].

O=S(C1=C(F)C=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(N)=NC=C4)SC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=N3)=C2F)=O

12352200