Daclatasvir-d16

MedChem Express

Daclatasvir-d16

10

Research Use Only

C40H34D16N8O6

754.97

Daclatasvir-d 16 is deuterium labeled Daclatasvir. Daclatasvir (BMS-790052) is a potent and orally active HCV NS5A protein inhibitor with EC50s range of 9-146 pM for multiple HCV replicon genotypes. Daclatasvir is also a organic anion transporting polypeptide 1B (OATP1B) and OATP1B3 inhibitor with IC50s of 1.5 microM and 3.27 microM, respectively[1][2][3].

O=C(C(NC(OC)=O)([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])N1CCC[C@H]1C2=NC=C(N2)C3=CC=C(C=C3)C4=CC=C(C5=CN=C([C@@H]6CCCN6C(C(NC(OC)=O)([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)N5)C=C4

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