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Dacomitinib hydrate [1042385-75-0]

Dacomitinib hydrate [1042385-75-0]

T19965
TargetMol Chemicals
CAS Number1042385-75-0
Product group Chemicals
Estimated Purity98.05%
Molecular Weight487.96
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Dacomitinib hydrate [1042385-75-0]
  • Delivery Days Customer
    4
  • CAS Number
    1042385-75-0
  • Certification
    Research Use Only
  • Chemical Name
    Dacomitinib hydrate
  • Estimated Purity
    98.05%
  • Molecular Formula
    C24H27ClFN5O3
  • Molecular Weight
    487.96
  • Scientific Description
    Dacomitinib hydrate (PF 299804) is a highly selective and second-generation small-molecule inhibitor of the pan-epidermal growth factor receptor family of tyrosine kinases. Dacomitinib specifically and irreversibly binds to and inhibits human EGFR subtypes, resulting in inhibition of proliferation and induction of apoptosis in EGFR-expressing tumor cells.
  • Shelf life instruction
    3 years
  • SMILES
    O.COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN1CCCCC1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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