Dactylocycline A [125622-12-0]

MedChem Express

Dactylocycline A [125622-12-0]

9

125622-12-0

Research Use Only

C31H40ClN3O13

698.11

Dactylocycline A is a tetracycline derivative with activity against some tetracycline-resistant microorganisms. Dactylocycline A is produced by fermentation of Dactylosporangium sp. and was found to be the most abundant glycoside in the initial fermentation. Dactylocycline A is acid-sensitive and readily hydrolyzes to the common sugar-free core substance dactylocyclinone. Although the sugar-free core has cross-resistance with tetracycline, Dactylocycline A exhibits activity against some tetracycline-resistant microorganisms[1].

O=C(N)C(C([C@@]1(O)C(O)=C2[C@@]([H])([C@](C)(C3=C(C(OC)=CC(O)=C3C2=O)Cl)O[C@@H]4O[C@@H](C)[C@H](OC)[C@](C4)(NO)C)C[C@@]1(O)[C@@H]5N(C)C)=O)=C5O

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