Dagrocorat

MedChem Express

Dagrocorat [1044535-52-5]

5

1044535-52-5

Research Use Only

99.90

C29H29F3N2O2

494.55

Dagrocorat (PF-00251802) is an orally active and selective high-affinity partial agonist of the glucocorticoid receptor . Dagrocorat is also a time-dependent reversible inhibitor of CYP3A ( IC 50 =1.3 microM in human liver microsomes) and CYP2D6 ( K i =0.57 microM in human liver microsomes). Dagrocorat can be used for the research of rheumatoid arthritis [1] .

O[C@@]1(C(F)(F)F)C[C@]2([H])[C@](C3=CC=C(C(NC(C=CC=N4)=C4C)=O)C=C3CC2)(CC1)CC5=CC=CC=C5

-20°C,2°C to 8°C

12352200