Dalotuzumab Biosimilar (Anti-IGF1R / CD221 Reference Antibody)

Biorbyt

Dalotuzumab Biosimilar (Anti-IGF1R / CD221 Reference Antibody)

10

Research Use Only

Monoclonal

Unconjugated

Dalotuzumab (MK-0646) is a recombinant humanized monoclonal antibody (IgG1 type) targeting IGF-1R. Dalotuzumab acts by inhibiting IGF-1- and IGF-2-mediated tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation. Dalotuzumab also induces apoptosis and cycle arrest. Dalotuzumab in combination with other anticancer agents such as statins can enhance the antitumor activity of Dalotuzumab in vitro and in vivo.

-20°C,2°C to 8°C

12352203