Dalotuzumab
ORB1980643
Product group Antibodies
Overview
- SupplierBiorbyt
- Product NameDalotuzumab
- Delivery Days Customer10
- CertificationResearch Use Only
- ClonalityMonoclonal
- ConjugateUnconjugated
- Estimated Purity98.00%
- Scientific DescriptionDalotuzumab (MK-0646) is a humanized recombinant monoclonal antibody (IgG1 type) that targets IGF-1R, inhibiting tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation mediated by IGF-1 and IGF-2. It induces apoptosis and cell cycle arrest, and its antitumor activity is significantly enhanced when used alongside other anticancer agents like statins, both in vitro and in vivo [1] [2] [3].
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203