Dalotuzumab [1005389-60-5]

TargetMol Chemicals

Dalotuzumab [1005389-60-5]

9

1005389-60-5

Research Use Only

Dalotuzumab

146.4 (kDa)

Dalotuzumab (MK-0646) is a humanized recombinant monoclonal antibody (IgG1 type) that targets IGF-1R, inhibiting tumor cell proliferation, IGF-1R autophosphorylation, and Akt phosphorylation mediated by IGF-1 and IGF-2. It induces apoptosis and cell cycle arrest, and its antitumor activity is significantly enhanced when used alongside other anticancer agents like statins, both in vitro and in vivo [1] [2] [3].

3 years

-20°C

12352203