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Dalpiciclib [1637781-04-4]
T9636
CAS Number1637781-04-4
Product group Chemicals
Estimated Purity98.32%
Molecular Weight446.54
Overview
- SupplierTargetMol Chemicals
- Product NameDalpiciclib [1637781-04-4]
- Delivery Days Customer4
- CAS Number1637781-04-4
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameDalpiciclib
- Estimated Purity98.32%
- Molecular FormulaC25H30N6O2
- Molecular Weight446.54
- Scientific DescriptionDalpiciclib (SHR-6390) is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4 nM and 9.9 nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
- Shelf life instruction3 years
- SMILESO=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)C4CCNCC4)N2)C5CCCC5
- Storage Instruction-20°C
- UNSPSC12352200