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Dalpiciclib [1637781-04-4]

Dalpiciclib [1637781-04-4]

T9636
TargetMol Chemicals
CAS Number1637781-04-4
Product group Chemicals
Estimated Purity98.32%
Molecular Weight446.54
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Dalpiciclib [1637781-04-4]
  • Delivery Days Customer
    4
  • CAS Number
    1637781-04-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Dalpiciclib
  • Estimated Purity
    98.32%
  • Molecular Formula
    C25H30N6O2
  • Molecular Weight
    446.54
  • Scientific Description
    Dalpiciclib (SHR-6390) is a highly selective, orally bioavailable, and comparable potency inhibitor of CDK4 and CKD6 with IC50s of 12.4 nM and 9.9 nM, respectively. Dalpiciclib exerts potent antitumor activity in esophageal squamous cell carcinoma by inhibiting phosphorylated tumor suppressor retinoblastoma protein (Rb) and inducing G1 cell cycle arrest.
  • Shelf life instruction
    3 years
  • SMILES
    O=C1N(C=2C(C(C)=C1C(C)=O)=CN=C(NC3=CC=C(C=N3)C4CCNCC4)N2)C5CCCC5
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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