DAN Polyclonal Antibody
RD75995A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetNBL1
Overview
- SupplierReddot Biotech
- Product NameDAN Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID4681
- Target nameNBL1
- Target descriptionNBL1, DAN family BMP antagonist
- Target synonymsD1S1733E; DAN; DAN domain family member 1; DAND1; differential screening-selected gene aberrant in neuroblastoma; NB; neuroblastoma 1, DAN family BMP antagonist; neuroblastoma candidate region, suppression of tumorigenicity 1; neuroblastoma suppressor of tumorigenicity 1; NO3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203