Dansylcadaverine [10121-91-2]

Chemodex

Dansylcadaverine [10121-91-2]

10

10121-91-2

Research Use Only

>98%

C17H25N3O2S

335.46

Chemical. CAS: 10121-91-2. Formula: C17H25N3O2S. MW: 335.46. Synthetic. Fluorescent probe for derivatization of aldehydes, ketones and carboxylic acids. Used to prepare small fluorescent biomolecules via amidation or reductive amination. Used to monitor autophagy. Functions by marking the autophagosomes, which allows researchers to follow the molecular components of the process throughout. Accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids. Has biological applications in measuring cardiac autophagic flux, studying Parkinsons disease, peritoneal ovarian tumor dissemination and respiratory diseases. This fluorescent tag is preferred over other due to its specificity and simplicity in detecting autophagic vesicles. Fluorescent substrate for assaying transamidating enzymes. Shown to inhibit endocytosis, the fibrin-stabilizing factor and epidermal growth factor (EGF) internalization. Dansyl dyes have environmentally sensitive fluorescence quantum yields and emission maxima along with large stokes shifts. Spectral Data: lambdaex 335nm; lambdaem518 nm in methanol. - Fluorescent probe for derivatization of aldehydes, ketones and carboxylic acids. Used to prepare small fluorescent biomolecules via amidation or reductive amination. Used to monitor autophagy. Functions by marking the autophagosomes, which allows researchers to follow the molecular components of the process throughout. Accumulates in autophagic vacuoles due to a combination of ion trapping and specific interactions with membrane lipids. Has biological applications in measuring cardiac autophagic flux, studying Parkinsons disease, peritoneal ovarian tumor dissemination and respiratory diseases. This fluorescent tag is preferred over other due to its specificity and simplicity in detecting autophagic vesicles. Fluorescent substrate for assaying transamidating enzymes. Shown to inhibit endocytosis, the fibrin-stabilizing factor and epidermal growth factor (EGF) internalization. Dansyl dyes have environmentally sensitive fluorescence quantum yields and emission maxima along with large stokes shifts. Spectral Data: lambdaex 335nm; lambdaem518 nm in methanol.

CN(C)C1=C(C=CC=C2S(NCCCCCN)(=O)=O)C2=CC=C1

-20°C

12352200