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Dantrolene (sodium hemiheptahydrate) [24868-20-0]

Research Use Only
HY-12542A
MedChem Express
CAS Number24868-20-0
Product group Chemicals
Estimated Purity99.79
Molecular Weight399.31
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Dantrolene (sodium hemiheptahydrate) [24868-20-0]
  • Delivery Days Customer
    9
  • CAS Number
    24868-20-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.79
  • Molecular Formula
    C14H10N4O5.7/2H2O.Na
  • Molecular Weight
    399.31
  • Scientific Description
    Dantrolene sodium hemiheptahydrate is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 microM and an IC50 of 52.3 microM. Dantrolene sodium hemiheptahydrate is a ryanodine receptor (RyR) antagonist and Ca2+ signaling stabilizer. Dantrolene sodium hemiheptahydrate is a direct-acting skeletal muscle relaxant. Dantrolene sodium hemiheptahydrate can be used for the research of muscle spasticity, malignant hyperthermia, Huntingtons disease and other neuroleptic malignant syndrome[1][2][3].
  • SMILES
    O=C1N([Na])C(CN1/N=C/C2=CC=C(C3=CC=C([N+]([O-])=O)C=C3)O2)=O.[3.5H2O]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200