Dantrolene (Standard)

MedChem Express

Dantrolene (Standard) [7261-97-4]

999

7261-97-4

Research Use Only

C14H10N4O5

314.25

Dantrolene (Standard) is the analytical standard of Dantrolene. This product is intended for research and analytical applications. Dantrolene is an orally active, non-competitive glutathione reductase inhibitor with a Ki of 111.6 microM and an IC50 of 52.3 microM. Dantrolene is a ryanodine receptor (RyR) antagonist and Ca2+ signaling stabilizer. Dantrolene is a direct-acting skeletal muscle relaxant. Dantrolene can be used for the research of muscle spasticity, malignant hyperthermia, Huntingtons disease and other neuroleptic malignant syndrome[1][2][3].

O=C1NC(CN1/N=C/C2=CC=C(C3=CC=C([N+]([O-])=O)C=C3)O2)=O

12352200