Bio-Connect

DAP5 antibody [C2C3], C-term

GTX101712
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetEIF4G2
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Overview

  • Supplier
    GeneTex
  • Product Name
    DAP5 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.39 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID1982
  • Target name
    EIF4G2
  • Target description
    eukaryotic translation initiation factor 4 gamma 2
  • Target synonyms
    AAG1; aging-associated protein 1; DAP5; DAP-5; death-associated protein 5; eIF4G 2; eIF-4G 2; eIF-4-gamma 2; eukaryotic translation initiation factor 4 gamma 2; eukaryotic translation initiation factor 4G-like 1; NAT1; P97
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP78344
  • Protein Name
    Eukaryotic translation initiation factor 4 gamma 2
  • Scientific Description
    Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203