Dapivirine-d4

MedChem Express

Dapivirine-d4

5

Research Use Only

C20H15D4N5

333.42

Dapivirine-d4 (TMC120-d4) is deuterium labeled Dapivirine. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[1][2][3].

N#CC1=C([2H])C([2H])=C(NC2=NC=CC(NC3=C(C)C=C(C)C=C3C)=N2)C([2H])=C1[2H]

12352200