
Western blot All lanes: DAPK2 antibody at 6microg/ml + Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 43, 56 kDa Observed band size: 43 kDa
DAPK2 Antibody
CSB-PA006500EA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
TargetDAPK2
Overview
- SupplierCusabio
- Product NameDAPK2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23604
- Target nameDAPK2
- Target descriptiondeath associated protein kinase 2
- Target synonymsDAP kinase 2; death-associated protein kinase 2; DRP1; DRP-1
- HostRabbit
- IsotypeIgG
- Protein IDQ9UIK4
- Protein NameDeath-associated protein kinase 2
- Scientific DescriptionCalcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203