Western blot All lanes: DAPK2 antibody at 6microg/ml + Mouse brain tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 43, 56 kDa Observed band size: 43 kDa

DAPK2 Antibody

CSB-PA006500EA01HU

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Mouse

TargetDAPK2

Overview

Supplier
Cusabio
Product Name
DAPK2 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID23604
Target name
DAPK2
Target description
death associated protein kinase 2
Target synonyms
DRP-1, DRP1, death-associated protein kinase 2, DAP kinase 2
Host
Rabbit
Isotype
IgG
Protein IDQ9UIK4
Protein Name
Death-associated protein kinase 2
Scientific Description
Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Isoform 2 is not regulated by calmodulin. It can phosphorylate MYL9. It can induce membrane blebbing and autophagic cell death.
Reactivity
Human, Mouse
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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DAPK2 Antibody

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