Darapladib

MedChem Express

Darapladib [356057-34-6]

10

356057-34-6

Research Use Only

99.94

C36H38F4N4O2S

666.77

Darapladib (SB-480848) is an orally active, selective and reversible Lp-PLA2 inhibitor ( IC 50 =0.25 nM). Darapladib can trigger irreversible actions on glioma cell apoptosis and induce cycle arrest. Darapladib can be used in the study of atherosclerosis and cancer [1] [2] [3] [4] .

FC1=CC=C(CSC(N(CC(N(CCN(CC)CC)CC2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)=O)C4=C5CCC4)=NC5=O)C=C1

-20°C,2°C to 8°C

12352200