Darunavir [206361-99-1]

MedChem Express

Darunavir [206361-99-1]

5

206361-99-1

Research Use Only

99.91

C27H37N3O7S

547.66

Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 microM; IC90 = 0.009 microM) with minimal cytotoxicity[1][2].

O=C(O[C@@H]1[C@@]2([H])[C@@](OCC2)([H])OC1)N[C@@H](CC3=CC=CC=C3)[C@H](O)CN(S(=O)(C4=CC=C(N)C=C4)=O)CC(C)C

-20°C,2°C to 8°C

12352200