Darunavir-d9 [1133378-37-6]

MedChem Express

Darunavir-d9 [1133378-37-6]

10

1133378-37-6

Research Use Only

C27H28D9N3O7S

556.72

Darunavir-d9 (TMC114-d9) is the deuterium labeled Darunavir. Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 microM; IC90 = 0.009 microM) with minimal cytotoxicity[1][2].

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12352200