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Dasatinib

HY-10181
MedChem Express
CAS Number302962-49-8
Product group Chemicals
Estimated Purity99.85
Molecular Weight488.017
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Dasatinib [302962-49-8]
  • Delivery Days Customer
    10
  • CAS Number
    302962-49-8
  • Certification
    Research Use Only
  • Estimated Purity
    99.85
  • Molecular Formula
    C22H26ClN7O2S
  • Molecular Weight
    488.017
  • Scientific Description
    Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The K i s are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC 50 s of [1] . Dasatinib also induces apoptosis and autophagy .
  • SMILES
    O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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