Dasatinib (monohydrate) (Standard)

MedChem Express

Dasatinib (monohydrate) (Standard) [863127-77-9]

5

Research Use Only

Dasatinib (monohydrate) (Standard) is the analytical standard of Dasatinib (monohydrate). This product is intended for research and analytical applications. Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC50s of [1] . Dasatinib monohydrate also induces apoptosis and autophagy.

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