DB04760 [544678-85-5]

MedChem Express

DB04760 [544678-85-5]

9

544678-85-5

Research Use Only

99.33

C22H20F2N4O2

410.42

DB04760 (compound 4) is a potent, highly selective, non-zinc-chelating MMP-13 inhibitor with an IC50 of 8 nM[1]. DB04760 significantly reduces paclitaxel neurotoxicity and has anticancer activity[2].

FC1=C(C=C(C=C1)CNC(C2=CC(C(NCC3=CC=C(C(C)=C3)F)=O)=NC=N2)=O)C

-20°C,2°C to 8°C

12352200