DB0614 [2769753-47-9]
HY-148063
CAS Number2769753-47-9
Product group Chemicals
Estimated Purity98.80
Molecular Weight822.95
Overview
- SupplierMedChem Express
- Product NameDB0614 [2769753-47-9]
- Delivery Days Customer10
- CAS Number2769753-47-9
- CertificationResearch Use Only
- Estimated Purity98.80
- Molecular FormulaC41H42N8O7S2
- Molecular Weight822.95
- Scientific DescriptionDB0614 is a PROTAC based on Cereblon ligand, which is a selective and potent targeted protein degrader of NEK9 inhibitor. DB0614 can degrade ABL1, ABL2, BLK, CDK11B, CDK4, CSK, EPHA3, FER, GAK, LIMK1, MAP3K20, MAP4K1, MAP4K2, MAP4K3, MAP4K5, MAPK14, MAPK7, MAPK8, MAPK9, MAPKAPK2, MAPKAPK3, NLK, PDIK1L, PTK2B, RIPK1, RPS6KA1, RPS6KA3, SIK2, SIK3, STK35, TNK2 and ULK1. DB0614 can be used for research of disease or disorder mediated by aberrant kinase activity[1][2].(Blue: Thalidomide-4-OH (HY-103596), Black: linker, Pink: FLT3-IN-17 (HY-148070))
- SMILESO=C1C2=C(C(N1C3C(NC(CC3)=O)=O)=O)C(OCCCCCN4CCN(CC4)C5=CC=C(NC6=NC7=C(SC=C7C8=CC(NS(=O)(C)=O)=CC=C8)C=N6)C=C5)=CC=C2
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12131703