DB1976 (dihydrochloride) [2369663-93-2]
HY-135797A
CAS Number2369663-93-2
Product group Chemicals
Estimated Purity98.0
Molecular Weight520.28
Overview
- SupplierMedChem Express
- Product NameDB1976 (dihydrochloride) [2369663-93-2]
- Delivery Days Customer9
- CAS Number2369663-93-2
- CertificationResearch Use Only
- Estimated Purity98.0
- Molecular FormulaC20H18Cl2N8Se
- Molecular Weight520.28
- Scientific DescriptionDB1976 dihydrochloride is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 dihydrochloride potently inhibits PU.1 binding (IC50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-lambdaB affinity, KD of 12 nM) in vitro. DB1976 dihydrochloride has apoptosis-inducing effect[1][2][3].
- SMILESN=C(C1=CC=C2N=C(C3=CC=C(C4=NC5=CC=C(C(N)=N)C=C5N4)[Se]3)NC2=C1)N.[H]Cl.[H]Cl
- Storage Instruction2°C to 8°C
- UNSPSC12352200
![DB1976 dihydrochloride [2369663-93-2]](https://www.targetmol.com/group3/M00/02/7A/CgoaEWY7Lv2EaPGOAAAAAAAtvkM964.png)