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ProductsBack/DBCO-NHCO-PEG4-amine [1255942-08-5]

DBCO-NHCO-PEG4-amine [1255942-08-5]

HY-124386
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DBCO-NHCO-PEG4-amine [1255942-08-5]
  • Delivery Days Customer
    10
  • CAS Number
    1255942-08-5
  • Certification
    Research Use Only
  • Molecular Formula
    C29H37N3O6
  • Molecular Weight
    523.62
  • Scientific Description
    DBCO-NHCO-PEG4-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. DBCO-NHCO-PEG4-amine is a cleavable ADC linker used to conjugate MMAE (HY-15162) and antibody (e.g., DBCO-VCpAB MMAE and DBCO-TRX MMAE with EC50s of 280 nM and 22 nM in SKBR3 cells, respectively)[1].
  • SMILES
    O=C(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)CCNC(CCOCCOCCOCCOCCN)=O
  • UNSPSC
    41115800

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