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ProductsBack/DBCO NHS ester [1384870-47-6]
DBCO NHS ester [1384870-47-6]

DBCO NHS ester [1384870-47-6]

Research Use Only
A270193
Antibodies.com
CAS Number1384870-47-6
Product group Chemicals
Estimated Purity95% (by 1H NMR and HPLC-MS).
Molecular Weight430.45 kDa
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Overview

  • Supplier
    Antibodies.com
  • Product Name
    DBCO NHS ester [1384870-47-6]
  • Delivery Days Customer
    7
  • CAS Number
    1384870-47-6
  • Certification
    Research Use Only
  • Estimated Purity
    95% (by 1H NMR and HPLC-MS).
  • Molecular Formula
    C25H22N2O5
  • Molecular Weight
    430.45 kDa
  • Scientific Description
    Dibenzocyclooctyne (ADIBO, DBCO) is one of the most reactive cycloalkynes for strain promoted alkyne azide cycloaddition (spAAC) - a copper free Click chemistry reaction. This is an amine-reactive NHS ester that provides easy attachment of the reactive moiety to almost any primary or secondary amine group, such as that of protein, peptide, or small molecule amine. DBCO reacts instantly with azides. The rate of the reaction is much higher than that of copper-catalyzed reaction, and reactions with many other cyclooctynes. Unlike some other cyclooctynes, DBCO does not react with tetrazines - this allows to carry out orthogonal conjugation of azides with DBCO, and trans-cyclooctenes with tetrazines.
  • Storage Instruction
    Shipped at room temperature. Upon delivery, store in the dark at -20°C. Avoid prolonged exposure to light. Desiccate.
  • UNSPSC
    12352200