DBCO-NHS ester 3

Biorbyt

DBCO-NHS ester 3 [1393350-27-0]

10

1393350-27-0

Research Use Only

98.00%

C24H20N2O5

416.43

DBCO-NHS ester 3 (Compound 12) is a cleavable linker utilized in the synthesis of antibody-drug conjugate (ADC). It is a derivative of Dibenzylcyclooctyne (DBCO) resulting from the activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2].

O=C(ON1C(=O)CCC1=O)CCCC(=O)N2C=3C=CC=CC3C#CC=4C=CC=CC4C2

-20°C

12352200