Bio-Connect

DBCO-PEG3-TCO

HY-133428
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DBCO-PEG3-TCO
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Estimated Purity
    98.0
  • Molecular Formula
    C36H45N3O7
  • Molecular Weight
    631.76
  • Scientific Description
    DBCO-PEG3-TCO is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. DBCO-PEG3-TCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. DBCO-PEG3-TCO also contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.
  • SMILES
    O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCNC(OC4CCC/C=C/CC4)=O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    41115800