DBeQ

BPS Bioscience

DBeQ

7

177355-84-9

Research Use Only

>98%

C22H20N4

340.4 Da

DBeQ is cell permeable, potent, selective and reversible inhibitor of the AAA-ATPase p97 (ATPase associated with diverse cellular activities). Ki=3.2 microM. DBeQ blocks both ubiquitin dependent and endoplasmic reticulum-associated degradation pathways, protein clearance pathways, and activates caspases -3 and -7 inducing apoptosis.

12352200