dBET1

AbMole BioScience

dBET1

9

1799711-21-9

Research Use Only

C38H37ClN8O7S

785.27

dBET1 is a potent BRD4 protein degrader with an EC50 of 430 nM. dBET1 is a PROTAC that composes of (+)-JQ1 linked to NSC 527179 with a linker.

CC1=C(C)C2=C(S1)[N]3C(=NN=C3C(CC(=O)NCCCCNC(=O)COC4=CC=CC5=C4C(=O)N(C6CCC(=O)NC6=O)C5=O)N=C2C7=CC=C(Cl)C=C7)C

12352200