Dbs antibody [N1N2], N-term

GeneTex

Dbs antibody [N1N2], N-term

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

MCF2L

MCF.2 cell line derived transforming sequence like

ARHGEF14; DBL's big sister; DBS; guanine nucleotide exchange factor DBS; MCF2 transforming sequence-like protein; OST

Rabbit

IgG

Guanine nucleotide exchange factor DBS

Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.

Human

-20°C or -80°C,2°C to 8°C

12352203