DBt-10

MedChem Express

DBt-10

14

Research Use Only

C68H86ClFN16O6

1277.97

DBt-10 is a potent BTK PROTAC degrader (DC50: 137 nM). Blue: DCAF1 binder (HY-149934); Black: linker; Pink: BTK ligand[1].

ClC(C=C1)=CC=C1C2(CCCCC2)C3=NC4=CC(N5CCN(C(CCCC(NCCN6CC7(CCN(C(CN8C=C(C9=CC(C(C%10=C(C)C(NC(N%11CC(CC(C)(C)C)(O)C%11)=O)=CC(F)=C%10)=NC=N%12)=C%12N9)C=N8)=O)CC7)OCC6)=O)=O)CC5)=CC=C4C(NCCN)=N3

12352200