DC44SMe [1354787-76-0]
HY-135124
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameDC44SMe [1354787-76-0]
- Delivery Days Customer10
- CAS Number1354787-76-0
- CertificationResearch Use Only
- Molecular FormulaC38H37ClN5O7PS2
- Molecular Weight806.29
- Scientific DescriptionDC44SMe, a phosphate proagent of cytotoxic DNA alkylator DC44, can be used in the synthesis of antibody-drug conjugate (ADC). DC44SMe exhibits IC50s of 2.0 nM, 2.8 nM, and 1.9 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC44SMe can be used for the targeted treatment of cancer[1].
- SMILESO=C(C(N1)=CC2=C1C=CC(NC(CCC(SSC)(C)C)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(OP(O)(O)=O)C7=CC=CC=C67)=O)=C4)C=C3
- UNSPSC41115800