DC4SMe [615538-47-1]
HY-135123
Product group Molecular Biology
Overview
- SupplierMedChem Express
- Product NameDC4SMe [615538-47-1]
- Delivery Days Customer10
- CAS Number615538-47-1
- CertificationResearch Use Only
- Molecular FormulaC35H31ClN5O7PS2
- Molecular Weight764.21
- Scientific DescriptionDC4SMe, a phosphate proagent of cytotoxic DNA alkylator DC4, can be used in the synthesis of antibody-drug conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer[1].
- SMILESO=C(C(N1)=CC2=C1C=CC(NC(CCSSC)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(OP(O)(O)=O)C7=CC=CC=C67)=O)=C4)C=C3
- UNSPSC41115800