DCB [6971-97-7]

MedChem Express

DCB [6971-97-7]

10

6971-97-7

Research Use Only

98.81

C14H10Cl2N2

277.15

DCB (3,3-dichlorobenzaldazine) is an neutral allosteric modulator of the metabotropic glutamate receptor metabotropic glutamate receptor subtype 5 (mGluR5). DCB blocks the positive allosteric regulation of mGluRs (mGluR5) with the help of 3,3-difluorobenzaldazine (DFB). DCB shows the negative modulatory effect of 3,3-dimethoxybenzaldazine (DMeOB)[1].

ClC1=CC(/C=N/N=C/C2=CC=CC(Cl)=C2)=CC=C1

-20°C

12352200