WB analysis of 293 cell lysate using GTX34348 DCC antibody.
WB analysis of 293 cell lysate using GTX34348 DCC antibody.
DCC antibody
GTX34348
Overview
- SupplierGeneTex
- Product NameDCC antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID1630
- Target nameDCC
- Target descriptionDCC netrin 1 receptor
- Target synonymscolorectal cancer suppressor; CRC18; CRCR1; deleted in colorectal carcinoma; HGPPS2; IGDCC1; immunoglobulin superfamily DCC subclass member 1; MRMV1; netrin receptor DCC; NTN1R1; putative colorectal tumor suppressor; tumor suppressor protein DCC
- HostRabbit
- IsotypeIgG
- Protein IDP43146
- Protein NameNetrin receptor DCC
- Scientific DescriptionThis gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203