DCDAPH [125113-96-4]

MedChem Express

DCDAPH [125113-96-4]

10

125113-96-4

Research Use Only

C16H15N3

249.31

DCDAPH (Compound 2c) is a novel smart NIRF probe for detection of beta-amyloid (Abeta) plaques (lambdaex/lambdaem=597/665 nm in PBS). DCDAPH shows high affinity for Abeta aggregates (Ki=37 nM, Kd=27 nM). DCDAPH shows good blood brain barrier permeation and can meet most of the requirements for the detection of Abeta plaques both in vitro and in vivo[1].

CN(C1=CC=C(/C=C/C=C/C=C(C#N)/C#N)C=C1)C

12162000