More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/DCPIB [82749-70-0]

DCPIB [82749-70-0]

Research Use Only
HY-103371
MedChem Express
CAS Number82749-70-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.83
Molecular Weight427.36
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    MedChem Express
  • Product Name
    DCPIB [82749-70-0]
  • Delivery Days Customer
    10
  • CAS Number
    82749-70-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C22H28Cl2O4
  • Molecular Weight
    427.36
  • Scientific Description
    DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 microM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 microM. DCPIB is a useful tool for investigating structure-function studies of K2P channels[1][2].
  • SMILES
    O=C(O)CCCOC1=CC2=C(C(C(C3CCCC3)(CCCC)C2)=O)C(Cl)=C1Cl
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200