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DCPIB

HY-103371
MedChem Express
CAS Number82749-70-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.83
Molecular Weight427.36
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Overview

  • Supplier
    MedChem Express
  • Product Name
    DCPIB [82749-70-0]
  • Delivery Days Customer
    10
  • CAS Number
    82749-70-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.83
  • Molecular Formula
    C22H28Cl2O4
  • Molecular Weight
    427.36
  • Scientific Description
    DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels ( VRAC ). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK , and inhibits TRESK , TASK1 and TASK3 ( IC 50 s: 0.14, 0.95, 50.72 microM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current ( I Cl,swell ), with an IC 50 of 4.1 microM. DCPIB is a useful tool for investigating structure-function studies of K2P channels [1] [2] .
  • SMILES
    O=C(O)CCCOC1=CC2=C(C(C(C3CCCC3)(CCCC)C2)=O)C(Cl)=C1Cl
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200