DcR1 antibody [TRAIL-R3-02] (Azide Free)

GeneTex

DcR1 antibody [TRAIL-R3-02] (Azide Free)

9

Flow Cytometry

Research Use Only

Monoclonal

TRAIL-R3-02

1 mg/ml

Unconjugated

TNFRSF10C

TNF receptor superfamily member 10c

antagonist decoy receptor for TRAIL/Apo-2L; CD263; cytotoxic TRAIL receptor-3; DCR1; DCR1-TNFR; decoy receptor 1; decoy TRAIL receptor without death domain; LIT; lymphocyte inhibitor of TRAIL; TNF-related apoptosis-inducing ligand receptor 3; TRAILR3; TRAIL-R3; TRID; tumor necrosis factor receptor superfamily member 10C; tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain

Mouse

IgG1

Tumor necrosis factor receptor superfamily member 10C

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]

2°C to 8°C

12352203