DCSTAMP Antibody, Biotin conjugated

Cusabio

DCSTAMP Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

DCSTAMP

dendrocyte expressed seven transmembrane protein

FIND, TM7SF4, hDC-STAMP, dendritic cell-specific transmembrane protein, DC-specific transmembrane protein, Dendritic cells (DC)-specific transmembrane protein, IL-4-induced protein, IL-Four (IL-4) induced, IL-Four INDuced, IL-four-induced protein, transmembrane 7 superfamily member 4

Rabbit

IgG

Dendritic cell-specific transmembrane protein

Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

Human

-20°C or -80°C

41116161