DCTN2 antibody

GeneTex

DCTN2 antibody

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

DCTN2

dynactin subunit 2

50 kDa dynein-associated polypeptide; DCTN50; dynactin 2 (p50); dynactin complex 50 kDa subunit; dynactin subunit 2; DYNAMITIN; epididymis secretory protein Li 77; epididymis secretory sperm binding protein; HEL-S-77; p50 dynamitin; RBP50

Rabbit

IgG

Dynactin subunit 2

This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203