DCTN3 Polyclonal Antibody

Elabscience

DCTN3 Polyclonal Antibody

12

ImmunoHistoChemistry

ELISA IHC

Research Use Only

Polyclonal

0.6 mg/ml

Unconjugated

DCTN3

dynactin subunit 3

DCTN-22, DCTN22, dynactin subunit 3, dynactin 3 (p22), dynactin complex subunit 22 kDa subunit, dynactin light chain

Rabbit

IgG

Dynactin subunit 3

This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.

-20°C

41116161