DCTN3 Polyclonal Antibody
RD75764A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetDCTN3
Overview
- SupplierReddot Biotech
- Product NameDCTN3 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.6 mg/ml
- ConjugateUnconjugated
- Gene ID11258
- Target nameDCTN3
- Target descriptiondynactin subunit 3
- Target synonymsDCTN22; DCTN-22; dynactin 3 (p22); dynactin complex subunit 22 kDa subunit; dynactin light chain; dynactin subunit 3
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants.
- ReactivityHuman
- Storage Instruction-20°C
- UNSPSC12352203