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Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using DCTN4 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using DCTN4 Polyclonal Antibody at dilution 1:30
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using DCTN4 Polyclonal Antibody at dilution 1:30

DCTN4 Polyclonal Antibody

Research Use Only
E-AB-14938
Elabscience
Product group Antibodies
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More than 130 suppliers
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Overview

  • Supplier
    Elabscience
  • Product Name
    DCTN4 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.6mg/ml
  • Scientific Description
    Dynactin is a multisubunit complex and a required cofactor for most, or all, of the cellular processes powered by the microtubule-based motor cytoplasmic dynein . Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end . The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin . In addition, Dynactin p62 is distributed in the nucleus at very high expression levels . Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton.
  • UNSPSC
    12352203