DCUN1D1 antibody [N2C3]
GTX116558
ApplicationsWestern Blot
Product group Antibodies
TargetDCUN1D1
Overview
- SupplierGeneTex
- Product NameDCUN1D1 antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID54165
- Target nameDCUN1D1
- Target descriptiondefective in cullin neddylation 1 domain containing 1
- Target synonymsDCNL1, DCUN1L1, RP42, SCCRO, SCRO, Tes3, DCN1-like protein 1, DCN1, defective in cullin neddylation 1, domain containing 1, DCUN1 domain-containing protein 1, RP42 homolog, defective in cullin neddylation protein 1-like protein 1, squamous cell carcinoma-related oncogene
- HostRabbit
- IsotypeIgG
- Protein IDQ96GG9
- Protein NameDCN1-like protein 1
- Scientific DescriptionPart of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wang J, Qian J, Hoeksema MD, et al. Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung. Clin Cancer Res. 2013,19(20):5580-90. doi: 10.1158/1078-0432.CCR-13-0594Read this paper






