DCUN1D1 antibody [N2C3]
GTX116558
Overview
- SupplierGeneTex
- Product NameDCUN1D1 antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID54165
- Target nameDCUN1D1
- Target descriptiondefective in cullin neddylation 1 domain containing 1
- Target synonymsDCN1, defective in cullin neddylation 1, domain containing 1; DCN1-like protein 1; DCNL1; DCUN1 domain-containing protein 1; DCUN1L1; defective in cullin neddylation protein 1-like protein 1; RP42; RP42 homolog; SCCRO; SCRO; squamous cell carcinoma-related oncogene; Tes3
- HostRabbit
- IsotypeIgG
- Protein IDQ96GG9
- Protein NameDCN1-like protein 1
- Scientific DescriptionPart of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Integrative genomics analysis identifies candidate drivers at 3q26-29 amplicon in squamous cell carcinoma of the lung. Wang J et al., 2013 Oct 15, Clin Cancer ResRead more