DDR1-IN-1 dihydrochloride [1780303-76-5]

MedChem Express

DDR1-IN-1 dihydrochloride [1780303-76-5]

10

1780303-76-5

Research Use Only

C30H33Cl2F3N4O3

625.51

DDR1-IN-1 dihydrochloride is a potent and selective DDR1 receptor tyrosine kinase inhibitor with an IC50 of 105 nM; 4-fold less potent for DDR2 (IC50 = 413 nM)[1].

CC1=C(C=C(C=C1)NC(C2=CC=C(C(C(F)(F)F)=C2)CN3CCN(CC3)CC)=O)OC4=CC(C5)=C(C=C4)NC5=O.Cl.Cl

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